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pentobarbital will lower the level or outcome of fostemsavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.Barbiturates can induce hepatic microsomal enzymes resulting in increased metabolism and lowered anticoagulant reaction of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); clients sta